The Little Rascals S01E12 - Giants Vs. Yanks

While the boys are playing their baseball game, a couple living nearby offer to take care of Jack's baby sister, Imogene. Eventually, the gang goes into their house when they realize there's a litter of puppies in there. By this time, however, the doctor has realized that one of the servants has a contagious disease and decides to quarantine the place, giving the gang a chance to turn the house into a disaster area.